How Smoking Affects Cancer Treatment, Recovery, and Survival Rates?

Around the world, a significant number of cancer patients smoke even after receiving a diagnosis. According to studies, up to two-thirds of cancer patients—including those with lung cancer, which is closely associated with tobacco use—continue to smoke following their diagnosis or while undergoing treatment.

It’s essential to be aware of the risks if you or a loved one is battling cancer and continues to smoke. In addition to explaining why it’s never too late to stop smoking, this article also discusses how continuing to smoke can worsen side effects, increase complications, lower survival rates, and negatively affect the results of cancer treatment.

Why Quitting Smoking After a Cancer Diagnosis Still Matters

Many smokers believe that once cancer is detected, the damage is already done. However, this couldn’t be further from reality. The Centers for Disease Control and Prevention (CDC) states that:

  • Your body starts healing just 20 minutes after your last cigarette.
  • 2–5 years after quitting, your risk of stroke drops to that of a non-smoker.
  • Ten years after quitting, your risk of lung cancer drops by 50%.

In other words, quitting even after receiving a diagnosis can increase your body’s ability to fight cancer and increase your chances of surviving it for a long time.

How Smoking Affects Cancer Treatment

Smoking doesn’t just cause cancer—it can actively interfere with your treatment in many ways.

What Makes Cancer Treatments Less Effective?

The U.S. Surgeon General states that smoking increases the failure rate of treatments across all cancer types.

  • Hypoxia (low oxygen levels): Smoking lowers blood oxygen levels, a condition known as hypoxia. This can result in worse treatment outcomes because treatments like immunotherapy and radiation therapy require oxygen-rich environments to function.
  • Modifies drug metabolism: Toxins in tobacco smoke may alter the way your body absorbs and processes chemotherapy, which could make it more toxic or less effective.
  • Weakens the immune system: Natural killer (NK) cells, which are essential for combating and containing cancer cells during treatment, are reduced in smokers.

What Common Issues Are Linked to Smoking During Treatment

Beyond impacting treatment efficacy, smoking is associated with several common issues that arise during treatment. These are

  • Shortness of breath, nausea, exhaustion, and increased pain.
  • Increased inflammation leads to greater overall discomfort.
  • Reduced dosage and more frequent breaks during treatment.
  • Poorer quality of life and mental health.

Increases Risk of Recurrence and Secondary Cancers

Myth: Once you get cancer from smoking, you can’t get it again.

Reality: Smoking increases your risk of multiple cancers, not just lung cancer.

Even after surviving one cancer, continued smoking  Raises

  • is the risk of pancreatic, esophageal, head and neck, and bladder cancers.
  • increases the likelihood that cancer will return
  • raises the death rate from secondary cancers

Smoking-related cancers include:

How to Quit Smoking

Quitting is difficult—but it’s possible, and help is available.

Most effective quit-smoking methods include

1. Nicotine Replacement Therapy (NRT): Uses gum, patches, inhalers, and lozenges that help reduce cravings and withdrawal symptoms.
2. Prescription Medications: Bupropion (Zyban) or varenicline (Chantix)  can reduce the pleasure associated with smoking and help with mood and motivation.
3. Counseling and Behavioral Therapy:  It includes individual or group sessions to enhance the success~35-40%—Global rate when combined with medication.

 Facts about Smoking & Cancer

Global Statistics

Statistic Global Data & Source
Smoking causes more than 8 million deaths per year globally  According to the World Health Organization (WHO), over 8 million people die each year due to tobacco use, more than 7 million from direct use and 1.3 million from secondhand smoke exposure. [WHO, 2024]
1 in 3 cancer deaths globally is linked to tobacco According to estimates from the American Cancer Society and the International Agency for Research on Cancer (IARC), tobacco use is responsible for between 30% and 35% of cancer-related deaths globally. [ACS, 2023]
80% of the world’s 1.3 billion tobacco users live in low- and middle-income countries Tobacco use burdens these countries with higher disease rates and lower access to care. [WHO, 2024]
Lung cancer is the most common cause of cancer death worldwide Lung cancer, which killed 1.8 million people worldwide in 2020, is mostly caused by tobacco use. [GLOBOCAN 2020]
Non-smokers are expected to live 10–12 years longer than smokers Large-scale global studies show smokers lose about a decade of life expectancy compared to non-smokers. [The Lancet, 2021]
Tobacco kills more people than alcohol, HIV/AIDS, malaria, and TB combined This makes it the leading preventable cause of death globally. [WHO, 2023]

In India

Statistic India Data & Source
Annual tobacco-related deaths ~13.5 lakh (1.35 million) — WHO India (2024)
% of all cancer deaths due to tobacco ~35- 40% — Global Burden of Disease, IHME (2024)
Lung cancer deaths in men are due to smoking ~90% — ICMR-NCDIR (2023)
Oral cancer cases from smokeless tobacco 83,400 (of 1.2 lakh global cases) — The Lancet / IARC (2022)
Overall cancer risk from tobacco (India) 2.7× higher — IARC Meta-analysis (2022)
Annual oral cancer deaths ~52,000 — Apollo Cancer Centres (2025)
Adult tobacco users in India 26.7 crore (267 million) — WHO-GATS 2 Survey (2016–17)
Projected tobacco-linked cancer burden 2.36 lakh by 2025 (~ increase by 40% since 2015) — ICMR-NCRP (2024)
Schoolchildren (13–15 yrs) using tobacco ~7.5-8.4% — WHO India (Youth Data) (2024)

Key Notes

  • 1 in 3 cancer deaths in India is linked to tobacco, per ICMR and GBD.
  • India has the 2nd highest number of tobacco users globally.
  • Smokeless tobacco plays a major role, making India the oral cancer capital of the world.
  • Tobacco triples cancer risk (×2.7), especially lung, head & neck, and oral cancers.

A Final Takeaway

Quitting smoking isn’t just a preventive measure—it plays a vital role in cancer treatment. For patients diagnosed with cancer, giving up tobacco can greatly improve how well treatments work, reduce the severity of side effects, lower the risk of cancer recurrence or developing a second cancer, and eventually improve survival rates. Even after a cancer diagnosis, it’s never too late to quit. Every cigarette you avoid gives your body a better opportunity to heal, respond to therapy, and recover more fully. Talk to your doctor, explore smoking cessation programs, and take the first step toward a healthier, smoke-free future.

FAQs 

Can you still benefit from quitting smoking after a cancer diagnosis?
Yes. Even after a diagnosis, stopping smoking can decrease the risk of recurrence or developing new cancers, improve treatment efficacy, and lessen side effects.

Does smoking make cancer symptoms worse?
Yes. Studies show that smokers have more pain, fatigue, nausea, and lower quality of life during cancer treatment.

Can continued smoking lead to another cancer after treatment?
Yes. Smoking after surviving one cancer greatly increases the risk of developing a second primary cancer in the same or a different organ.

How long after quitting does cancer risk decrease?
Risk of stroke drops to that of a non-smoker in 2–5 years; lung cancer risk is halved in 10 years after quitting.

Does smoking affect surgery recovery in cancer patients?
Yes. Smoking reduces blood flow, weakens immunity, and slows wound healing, increasing post-surgical complications.

Can I use vaping or e-cigarettes while undergoing cancer treatment?
Vaping is not a safe alternative. Many e-cigarettes contain harmful substances that may interfere with healing and cancer treatment.

Busted: 7 Myths About Smoking and Cancer

Whether you are trying to save money, managing a health diagnosis like cancer, or expecting a child, quitting…

You May Also Like

Book your Consultation with Denvax

Leaders in Immunotherapy!